SCHEMBL24510522

SCHEMBL24510522

O=C1NC[C@@]2(O)CNCC[C@@H]12

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24510480 1.00 OPRM1 (0.30) OPRM1OPRL1
SCHEMBL24510335 1.00 OPRM1 (0.30) OPRM1OPRL1
SCHEMBL24510435 0.72
SCHEMBL24510428 0.72
SCHEMBL19770250 0.71 CCR2 (0.39) OPRM1OPRL1
SCHEMBL30497373 0.71 OPRM1 (0.34) OPRM1OPRL1
SCHEMBL30497346 0.71 OPRM1 (0.34) OPRM1OPRL1
SCHEMBL24510993 0.69 CHRM2 (0.30)
SCHEMBL24510982 0.69 CHRM2 (0.30)
SCHEMBL24510935 0.69 CHRM2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115003673-A Dihydropyrimidine compound, and preparation method and application thereof 上海维申医药有限公司 2022-09-02 CN disclosed
WO-2022121844-A1 DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 上海维申医药有限公司 2022-06-16 WO disclosed
CN-114621219-A Dihydropyrimidine compound, and preparation method and application thereof 上海维申医药有限公司 2022-06-14 CN disclosed