Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | BRD2 | P25440 | 4/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29717158 | 0.92 | CNR1 (0.41) | CNR1CNR2MAOBMAPTPOLB | |
| SCHEMBL24512243 | 0.92 | CNR1 (0.41) | CNR1CNR2MAOBMAPTPOLB | |
| SCHEMBL24512121 | 0.79 | CNR1 (0.46) | CNR1CNR2MAOBMAPTBRD4 | |
| SCHEMBL24512359 | 0.79 | CNR1 (0.46) | CNR1CNR2MAOBMAPTBRD4 | |
| SCHEMBL29717135 | 0.78 | CNR1 (0.48) | CNR1CNR2MAPTPOLBBRD4 | |
| SCHEMBL24512334 | 0.78 | CNR1 (0.48) | CNR1CNR2MAPTPOLBBRD4 | |
| SCHEMBL29717201 | 0.75 | LMNA (0.55) | CNR1CNR2MAPTBRD4BRD2 | |
| SCHEMBL29717142 | 0.75 | LMNA (0.52) | CNR1CNR2MAPTBRD4BRD2 | |
| SCHEMBL27199057 | 0.75 | CNR2 (0.48) | CNR1CNR2MAPTPOLBBRD4 | |
| SCHEMBL24512244 | 0.75 | CNR1 (0.43) | CNR1CNR2MAOBMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125989-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | SCRIPPS RESEARCH INSTITUTE, THE (US) | 2022-06-16 | — | — | WO | disclosed |