Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 4/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20462535 | 0.90 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1ALDH1A1IMPDH2 | |
| SCHEMBL20462521 | 0.90 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1ALDH1A1IMPDH2 | |
| SCHEMBL20462537 | 0.90 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1ALDH1A1IMPDH2 | |
| SCHEMBL20462507 | 0.90 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1ALDH1A1IMPDH2 | |
| SCHEMBL20462522 | 0.90 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1ALDH1A1IMPDH2 | |
| SCHEMBL22087964 | 0.90 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL22990582 | 0.90 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL20225058 | 0.90 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL20434918 | 0.90 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL21393001 | 0.88 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125984-A1 | TAU-TARGETING OLIGONUCLEOTIDE GAPMERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2022-06-16 | — | — | WO | disclosed |