Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393002 | 0.94 | TAS1R3 (0.48) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL22990582 | 0.94 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL20225058 | 0.94 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL20434918 | 0.94 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL22087964 | 0.92 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL22524143 | 0.88 | TAS1R3 (0.47) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL18963691 | 0.88 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL24513564 | 0.88 | KDM4E (0.52) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL21636978 | 0.87 | KDM4E (0.51) | KDM4ETAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL21393210 | 0.86 | KDM4E (0.60) | KDM4ETAS1R3TAS1R1POLBIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-B1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| EP-3854799-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |