Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 7/20 | 0.45 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20434918 | 1.00 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 | |
| SCHEMBL20225058 | 1.00 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 | |
| SCHEMBL21393001 | 0.94 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 | |
| SCHEMBL22087964 | 0.93 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 | |
| SCHEMBL18963691 | 0.90 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 | |
| SCHEMBL24513564 | 0.90 | KDM4E (0.52) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 | |
| SCHEMBL21636978 | 0.89 | KDM4E (0.51) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 | |
| SCHEMBL22087557 | 0.88 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 | |
| SCHEMBL15688224 | 0.88 | TAS1R3 (0.55) | TAS1R3TAS1R1IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL21393002 | 0.87 | TAS1R3 (0.48) | KDM4ETAS1R3TAS1R1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512861-B1 | CYCLIC DINUCLEOTIDES AS STING (STIMULATOR OF INTERFERON GENES) AGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-02-17 | — | — | EP | disclosed |