⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245135 | 0.81 | NOS3 (0.50) | — | |
| SCHEMBL5640712 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL1845719 | 0.77 | NOS3 (0.46) | — | |
| SCHEMBL14218666 | 0.77 | — | — | |
| SCHEMBL7615368 | 0.77 | — | — | |
| SCHEMBL27013272 | 0.77 | — | — | |
| SCHEMBL2113502 | 0.74 | PKM (0.35) | — | |
| SCHEMBL28171100 | 0.74 | — | — | |
| SCHEMBL12048608 | 0.74 | KDM4E (0.45) | — | |
| SCHEMBL1583838 | 0.74 | NOS3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | claimed |
| US-20040132981-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-07-08 | — | — | US | claimed |
| CN-1418111-A | Novel Ligands and method for preparing same | NAT UNIV SINGAPORE (SG) | 2003-05-14 | — | — | CN | claimed |
| EP-1289561-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-03-12 | — | — | EP | claimed |
| US-20010051348-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-12-13 | — | — | US | claimed |
| WO-2001054731-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-08-02 | — | — | WO | claimed |
| CN-119455004-A | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119455003-A | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113660957-B | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118786140-A | Anti-SARS-CoV-2 spike (S) antibodies and their use in treatment COVID-19 | 诺瓦瓦克斯股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-117440833-A | anti-HER 2 antibody-drug conjugates and uses thereof | AMBRX公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-109313200-B | Bioanalytical methods for characterizing site-specific antibody-drug conjugates | 豪夫迈·罗氏有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-109071657-B | Pharmaceutical compositions comprising bispecific antibody constructs | 安进研发（慕尼黑）股份有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-1137826-A | Method and compositions for treatment of BCR-ABL associated leukemias and other cell proliferative disorders | NEW YORK UNIV MEDICAL CENTER (US) | 1996-12-11 | — | — | CN | disclosed |
| US-5468480-A | Active against N-A-benzoyl-DL-arginine p-nitroanilide | THE BOOTS COMPANY PLC (GB) | 1995-11-21 | — | — | US | disclosed |
| US-5380656-A | Chymopapain and method of purifying it on an inhibitory dipeptide affinity column | THE BOOTS COMPANY PLC (GB) | 1995-01-10 | — | — | US | disclosed |
| EP-0470136-B1 | THERAPEUTIC AGENT | BOOTS CO PLC (GB) | 1994-06-22 | — | — | EP | disclosed |
| EP-0470136-A1 | THERAPEUTIC AGENT. | BOOTS CO PLC (GB) | 1992-02-12 | — | — | EP | disclosed |
| CN-1047340-A | Therapeutical agent | BOOTS CO PLC (GB) | 1990-11-28 | — | — | CN | disclosed |
| WO-1990013561-A1 | THERAPEUTIC AGENT | THE BOOTS COMPANY PLC (GB) | 1990-11-15 | — | — | WO | disclosed |