Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24513629 | 0.87 | GAA (0.42) | KDM4EALDH1A1DRD3L3MBTL1PREP | |
| SCHEMBL614621 | 0.86 | PREP (0.47) | KDM4EALDH1A1PREPRAB9AMAOB | |
| SCHEMBL6770995 | 0.84 | PREP (0.46) | KDM4EALDH1A1PREPRAB9AMAOB | |
| SCHEMBL578484 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1NOS1DRD4DRD2 | |
| SCHEMBL2474081 | 0.81 | ALDH1A1 (0.54) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL2607317 | 0.80 | PREP (0.51) | KDM4EALDH1A1L3MBTL1TDP1PREP | |
| SCHEMBL7898603 | 0.80 | ATM (0.58) | KDM4EALDH1A1NOS1DRD4DRD2 | |
| SCHEMBL17465617 | 0.80 | ATM (0.58) | KDM4EALDH1A1NOS1DRD4DRD2 | |
| SCHEMBL12703827 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1RECQLPREP | |
| SCHEMBL6763899 | 0.78 | PREP (0.53) | KDM4EALDH1A1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122780-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2022-06-16 | — | — | WO | disclosed |