Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | DUT | P33316 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474081 | 0.92 | ALDH1A1 (0.54) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL20204806 | 0.83 | MAPT (0.47) | KDM4EALDH1A1DUTTDP1MAPK1 | |
| SCHEMBL24513630 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL25369942 | 0.83 | LTA4H (0.50) | DRD4DRD2DRD3DUT | |
| SCHEMBL20568979 | 0.83 | APP (0.41) | KDM4EALDH1A1DUT | |
| SCHEMBL20569831 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1DUTL3MBTL1MAPK1 | |
| SCHEMBL25401134 | 0.83 | CHRNB2 (0.38) | KDM4EALDH1A1DUT | |
| SCHEMBL31637830 | 0.83 | CHRNB2 (0.38) | KDM4EALDH1A1DUT | |
| SCHEMBL20569059 | 0.81 | DUT (0.39) | KDM4EALDH1A1DUTMAOBDHFR | |
| SCHEMBL1629693 | 0.81 | HRH3 (0.43) | KDM4EALDH1A1DUTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846978-B2 | Electronic devices comprising novel phosphonic acid surface modifiers | IMPERIAL INNOVATIONS LTD. (GB) | 2014-09-30 | — | — | US | disclosed |
| US-8822503-B2 | 2-pyridone compounds | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2014-09-02 | — | — | US | disclosed |
| US-8586208-B2 | Stable electrodes with modified work functions and methods for organic electronic devices | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120114974-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | NATIONAL SCIENCE FOUNDATION | 2012-05-10 | — | — | US | disclosed |
| EP-2417142-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | Georgia Tech Research Corporation (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20110237791-A1 | 2-PYRIDONE COMPOUNDS | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110114935-A1 | Stable electrodes with modified work functions and methods for organic electronic devices | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-05-19 | — | — | US | disclosed |
| EP-2304820-A1 | STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES | Georgia Tech Research Corporation (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010115854-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010007081-A1 | STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110114935-A1 | Stable electrodes with modified work functions and methods for organic electronic devices | EPCAM, EMD, L1CAM | KDM4E 484/4885ALDH1A1 1848/4885DRD4 2044/4885 |
| US-20110237791-A1 | 2-PYRIDONE COMPOUNDS | PDXK, HK1, KCNJ2 | KDM4E 871/4885ALDH1A1 2239/4885DRD4 2000/4885 |
| US-20120114974-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | EFNA1, PHOSPHO1, EPHA6 | KDM4E 1389/4885ALDH1A1 2641/4885DRD4 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.