Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4998283 | 0.98 | TSHR (0.39) | TSHR | |
| SCHEMBL595648 | 0.79 | — | — | |
| SCHEMBL347199 | 0.76 | — | — | |
| SCHEMBL8621409 | 0.69 | TSHR (0.43) | TSHR | |
| SCHEMBL22109759 | 0.69 | TSHR (0.43) | TSHR | |
| SCHEMBL22470021 | 0.67 | ALDH1A1 (0.33) | CDC7DBF4 | |
| SCHEMBL15155134 | 0.67 | CA1 (0.61) | TSHR | |
| SCHEMBL8047024 | 0.67 | CA1 (0.50) | TSHR | |
| SCHEMBL11366827 | 0.67 | CA1 (0.50) | TSHR | |
| SCHEMBL6283784 | 0.67 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732899-B1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S R L (IT) | 2011-09-21 | — | — | EP | disclosed |
| US-7381823-B2 | Process for preparing cyclohexanediacetic acid monoamide | SERICHIM S.R.L. (IT) | 2008-06-03 | — | — | US | disclosed |
| US-20070208175-A1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S.R.L. (IT) | 2007-09-06 | — | — | US | disclosed |
| EP-1753733-A1 | SMALL MOLECULES FOR TREATMENT OF HYPERCHOLESTEROLEMIA AND RELATED DISEASES | Avanir Pharmaceuticals (US) | 2007-02-21 | — | — | EP | disclosed |
| EP-1732899-A2 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHUM S.R.L. (IT) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005123700-A1 | SMALL MOLECULES FOR TREATMENT OF HYPERCHOLESTEROLEMIA AND RELATED DISEASES | AVANIR PHARMACEUTICALS (US) | 2005-12-29 | — | — | WO | disclosed |
| WO-2005090310-A2 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | SERICHIM S.R.L. (IT) | 2005-09-29 | — | — | WO | disclosed |
| US-5369110-A | Hypotensive agents, cardiac insufficiency treatment | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208175-A1 | PROCESS FOR PREPARING CYCLOHEXANEDIACETIC ACID MONOAMIDE | GNPAT, GMDS, PIGS | TSHR 4706/4885CDC7 859/4885DBF4 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.