Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145378 | 1.00 | LNPEP (0.50) | LNPEPERAP2EPHX2NR1H4BACE1 | |
| SCHEMBL24514049 | 0.89 | LNPEP (0.46) | LNPEPERAP2BACE1HDAC8ANPEP | |
| SCHEMBL29145375 | 0.89 | LNPEP (0.46) | LNPEPERAP2BACE1HDAC8ANPEP | |
| SCHEMBL24513869 | 0.88 | CA1 (0.47) | LNPEPERAP2BACE1HDAC8ANPEP | |
| SCHEMBL29145408 | 0.88 | CA1 (0.47) | LNPEPERAP2BACE1HDAC8ANPEP | |
| SCHEMBL24514043 | 0.85 | LNPEP (0.53) | LNPEPERAP2BACE1HDAC8ANPEP | |
| SCHEMBL29145409 | 0.85 | LNPEP (0.53) | LNPEPERAP2BACE1HDAC8ANPEP | |
| SCHEMBL7289465 | 0.85 | BACE1 (0.60) | LNPEPERAP2BACE1HDAC8MEN1 | |
| SCHEMBL7289459 | 0.85 | BACE1 (0.60) | LNPEPERAP2BACE1HDAC8MEN1 | |
| Hydrochloric Acid SCHEMBL28974655 | 0.83 | BACE1 (0.58) | LNPEPERAP2BACE1HDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122035-A1 | COAGULATION FACTOR XIA INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2022-06-16 | — | — | WO | disclosed |
| WO-2022122035-A1 | COAGULATION FACTOR XIA INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2022-06-16 | — | — | WO | disclosed |