Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24514049 | 1.00 | LNPEP (0.46) | LNPEPERAP2CA1CA2BACE1 | |
| SCHEMBL29145408 | 0.97 | CA1 (0.47) | LNPEPERAP2CA1CA2BACE1 | |
| SCHEMBL24513869 | 0.97 | CA1 (0.47) | LNPEPERAP2CA1CA2BACE1 | |
| SCHEMBL24513853 | 0.89 | LNPEP (0.50) | LNPEPERAP2CA1CA2BACE1 | |
| SCHEMBL29145378 | 0.89 | LNPEP (0.50) | LNPEPERAP2CA1CA2BACE1 | |
| SCHEMBL24514043 | 0.80 | LNPEP (0.53) | LNPEPERAP2BACE1HDAC8ROCK2 | |
| SCHEMBL29145409 | 0.80 | LNPEP (0.53) | LNPEPERAP2BACE1HDAC8ROCK2 | |
| SCHEMBL7289465 | 0.80 | BACE1 (0.60) | LNPEPERAP2BACE1HDAC8NAMPT | |
| SCHEMBL7289459 | 0.80 | BACE1 (0.60) | LNPEPERAP2BACE1HDAC8NAMPT | |
| Hydrochloric Acid SCHEMBL28974655 | 0.79 | BACE1 (0.58) | LNPEPERAP2BACE1HDAC8NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480164-B | Factor XIa inhibitor and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-117480164-A | Factor XIa inhibitor and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-01-30 | — | — | CN | disclosed |