Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052929 | 0.97 | ABCB1 (0.69) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL7156543 | 0.97 | ABCB1 (0.69) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL24514601 | 0.95 | ABCB1 (0.73) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL8068919 | 0.95 | ABCB1 (0.73) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL4649969 | 0.95 | ABCB1 (0.73) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL24514598 | 0.92 | ABCB1 (0.68) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL6904467 | 0.91 | ABCB1 (0.70) | ABCB1MEN1KMT2AABCG2L3MBTL1 | |
| SCHEMBL8062100 | 0.89 | MEN1 (0.71) | ABCB1MEN1KMT2AABCG2L3MBTL1 | |
| SCHEMBL8062122 | 0.89 | ABCB1 (0.64) | ABCB1MEN1KMT2AABCG2TP53 | |
| SCHEMBL21206267 | 0.88 | ABCB1 (0.73) | ABCB1MEN1KMT2AABCG2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |