SCHEMBL24514736

SCHEMBL24514736

BrC1=CCC(c2ccccc2)S1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.35
GSK3B P49841 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
MAOA P21397 6/20 0.31
MAOB P27338 6/20 0.31
KDM1A O60341 4/20 0.31
CYP2C19 P33261 4/20 0.31
CYP2B6 P20813 3/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2D6 P10635 2/20 0.31
CYP2C9 P11712 2/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9925856 0.75 ALDH1A1 (0.36) TSHRHSD17B10SMN1; SMN2ALDH1A1GSK3B
SCHEMBL28529394 0.64
SCHEMBL383636 0.64
SCHEMBL20601589 0.62 SLC18A3 (0.41) TSHRHSD17B10MAOAMAOBKDM1A
SCHEMBL15570404 0.61 BRD4 (0.46) TSHRHSD17B10MAOAMAOBKDM1A
SCHEMBL13225362 0.61 TSHR (0.39) TSHRHSD17B10SMN1; SMN2ALDH1A1MAOA
SCHEMBL9490322 0.60 SMN1; SMN2 (0.51) TSHRHSD17B10SMN1; SMN2ALDH1A1GSK3B
SCHEMBL6414384 0.60 TSHR (0.36) TSHRHSD17B10SMN1; SMN2ALDH1A1CRHBP
SCHEMBL2031804 0.59 HDAC4 (0.46) TSHRHSD17B10MAOAMAOBKDM1A
SCHEMBL31041077 0.59 HDAC4 (0.46) TSHRHSD17B10MAOAMAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022124516-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG Display Co.,Ltd. (KR) 2022-06-16 WO disclosed