Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5848587 | 0.98 | TSHR (0.35) | TSHRALDH1A1SMN1; SMN2HSD17B10SLC18A3 | |
| SCHEMBL44650 | 0.75 | SIGMAR1 (0.44) | TSHRALDH1A1SMN1; SMN2HSD17B10SIGMAR1 | |
| SCHEMBL20601589 | 0.74 | SLC18A3 (0.41) | TSHRHSD17B10SLC18A3SIGMAR1CYP11B2 | |
| SCHEMBL10534331 | 0.67 | KDM1A (0.41) | SMN1; SMN2SIGMAR1CRHBPCRHR2MAOA | |
| SCHEMBL15570404 | 0.67 | BRD4 (0.46) | TSHRHSD17B10SLC18A3SIGMAR1MAOA | |
| SCHEMBL9872211 | 0.67 | ALDH1A1 (0.38) | TSHRALDH1A1SMN1; SMN2HSD17B10SLC18A3 | |
| SCHEMBL10109189 | 0.67 | SLC18A3 (0.35) | TSHRSLC18A3SIGMAR1MAOAMAOB | |
| SCHEMBL383636 | 0.66 | — | — | |
| SCHEMBL28529394 | 0.66 | — | — | |
| SCHEMBL2403745 | 0.65 | GAA (0.38) | TSHRALDH1A1SMN1; SMN2HSD17B10CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559399-A1 | Use of 2-iminothiolane derivatives in hair care products | L'OREAL (FR) | 2005-08-03 | — | — | EP | claimed |
| EP-1559399-A1 | Use of 2-iminothiolane derivatives in hair care products | L'OREAL (FR) | 2005-08-03 | — | — | EP | disclosed |