Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24515081 | 0.82 | ALDH1A1 (0.37) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL3754107 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL19493622 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL19493632 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL21917349 | 0.72 | SLC6A2 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL16649635 | 0.71 | SLC6A2 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL10599869 | 0.70 | PNMT (0.44) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL22032277 | 0.69 | AHR (0.46) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL1154655 | 0.69 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 | |
| SCHEMBL20238211 | 0.69 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125735-A1 | PROCESSES FOR MAKING PRMT5 INHIBITORS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-06-16 | — | — | WO | disclosed |