SCHEMBL24514949

SCHEMBL24514949

BC1=CC=C(c2ccccc2)C1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CFTR P13569 1/20 0.34
GOPC Q9HD26 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
HTR2C P28335 1/20 0.33
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3982745 0.82 ALDH1A1 (0.47) ALDH1A1CFTRGOPCSIGMAR1HTR2C
SCHEMBL17209233 0.81 ALDH1A1 (0.36) ALDH1A1CFTRGOPCSIGMAR1HTR2C
SCHEMBL14192246 0.71 CYP3A4 (0.64) ALDH1A1NPC1RAB9AKDM4EGLA
SCHEMBL457003 0.70 ALDH1A1 (0.33) ALDH1A1CFTRGOPCSIGMAR1MAPK1
SCHEMBL21625337 0.70 NPC1 (0.45) ALDH1A1NPC1RAB9AKDM4EMAPT
SCHEMBL17147181 0.70 PTGS1 (0.43) ALDH1A1SIGMAR1HTR2CNPC1RAB9A
SCHEMBL8686264 0.69 CHRNB4 (0.44) ALDH1A1SIGMAR1HTR2CNPC1RAB9A
SCHEMBL8686265 0.69 CHRNB4 (0.44) ALDH1A1SIGMAR1HTR2CNPC1RAB9A
SCHEMBL23260378 0.67 PTPN1 (0.33) ALDH1A1CFTRGOPCSIGMAR1HTR2C
SCHEMBL893700 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022124516-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG Display Co.,Ltd. (KR) 2022-06-16 WO disclosed