Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982745 | 0.85 | ALDH1A1 (0.47) | KDM4ESIGMAR1CYP3A4TAAR1HSD17B10 | |
| SCHEMBL14192246 | 0.79 | CYP3A4 (0.64) | KDM4EMAOAMAOBCYP3A4TAAR1 | |
| SCHEMBL8681494 | 0.78 | MAPK14 (0.41) | PTGS1PTGS2MAOBNPC1RAB9A | |
| SCHEMBL21625337 | 0.77 | NPC1 (0.45) | KDM4EMAOAMAOBTDP1NPC1 | |
| SCHEMBL12444110 | 0.77 | ALDH1A1 (0.60) | PTGS1PTGS2NFE2L2CYP3A4TAAR1 | |
| SCHEMBL412237 | 0.77 | ALDH1A1 (0.60) | PTGS1PTGS2NFE2L2CYP3A4TAAR1 | |
| SCHEMBL7938359 | 0.77 | ALDH1A1 (0.60) | PTGS1PTGS2NFE2L2CYP3A4TAAR1 | |
| SCHEMBL456797 | 0.77 | ALDH1A1 (0.33) | SIGMAR1ALDH1A1 | |
| SCHEMBL17147187 | 0.76 | ACHE (0.39) | PTGS1PTGS2NFE2L2MAOBTDP1 | |
| Water SCHEMBL6337149 | 0.75 | ALDH1A1 (0.56) | PTGS1PTGS2NFE2L2CYP3A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701771-B2 | Substituted zirconocenes catalysts and methods of use in polymerization reactions | BASELL POLYOLEFINE GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-9701771-B2 | Substituted zirconocenes catalysts and methods of use in polymerization reactions | BASELL POLYOLEFINE GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-9422380-B2 | Non-bridged metallocene complexes for the polymerization of olefins | Basell Polyolefine Wesseling (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422380-B2 | Non-bridged metallocene complexes for the polymerization of olefins | Basell Polyolefine Wesseling (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422319-B2 | Bisaryl metallocenes and use thereof to produce polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422319-B2 | Bisaryl metallocenes and use thereof to produce polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284490-A1 | SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284490-A1 | SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS | BASELL POLYOLEFIN GMBH (DE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284418-A1 | BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS | PCBP1, PARG, PARN | PTGS1 3548/4885PTGS2 2037/4885KDM4E 3356/4885 |
| US-20150284490-A1 | SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS | MAOA, MPO, PARP1 | PTGS1 2569/4885PTGS2 1679/4885KDM4E 1471/4885 |
| US-20150284489-A1 | NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS | PCBP1, MORF4L1, PPIL4 | PTGS1 2480/4885PTGS2 2298/4885KDM4E 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.