Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.56 |
| ▸ | TUBB | P07437 | 4/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24517687 | 0.86 | NPC1 (0.54) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24517305 | 0.85 | KDM4E (0.53) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24517309 | 0.85 | ALDH1A1 (0.53) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22615094 | 0.84 | RAB9A (0.62) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24517390 | 0.83 | RAD51 (0.43) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24517330 | 0.82 | PLAU (0.46) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24517108 | 0.82 | KDM4E (0.44) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24517691 | 0.81 | NTRK1 (0.46) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24516940 | 0.81 | ADORA1 (0.43) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24517326 | 0.80 | RAB9A (0.46) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185822-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185822-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | NR1I2, NR1H2, NR1H4 | NPC1 366/4885RAB9A 4268/4885KDM4E 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.