Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31394486 | 1.00 | PTGDR2 (0.37) | PTGDR2SLC6A4SLC6A2ABHD6MAPK1 | |
| SCHEMBL24517233 | 0.86 | PTGDR2 (0.37) | PTGDR2SLC6A4SLC6A2ABHD6MAPK1 | |
| SCHEMBL28758461 | 0.80 | PTGDR2 (0.36) | PTGDR2SLC6A4SLC6A2MAPK1HSD17B10 | |
| SCHEMBL24517236 | 0.77 | — | — | |
| SCHEMBL6673940 | 0.77 | PTGDR2 (0.40) | PTGDR2SLC6A4SLC6A2NPC1ALDH1A1 | |
| SCHEMBL610591 | 0.77 | PDE2A (0.40) | ABHD6NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL23094690 | 0.77 | ALOX15 (0.39) | SLC6A2ABHD6HPGDLMNA | |
| SCHEMBL31393937 | 0.77 | PTGDR2 (0.40) | PTGDR2SLC6A4SLC6A2NPC1ALDH1A1 | |
| SCHEMBL19839324 | 0.77 | PDE2A (0.40) | ABHD6NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL29395891 | 0.77 | PDE2A (0.40) | ABHD6NPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022121805-A1 | FUSED RING COMPOUND AS NAV1.8 INHIBITOR AND USE THEREOF | 成都康弘药业集团股份有限公司 | 2022-06-16 | — | — | WO | disclosed |