Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758473 | 0.87 | PTGDR2 (0.33) | PTGDR2ADRB2 | |
| SCHEMBL29618373 | 0.87 | PTGDR2 (0.33) | PTGDR2ADRB2 | |
| SCHEMBL24517232 | 0.80 | PTGDR2 (0.37) | PTGDR2SLC6A2SLC6A4ADRB2MAPK1 | |
| SCHEMBL31394486 | 0.80 | PTGDR2 (0.37) | PTGDR2SLC6A2SLC6A4ADRB2MAPK1 | |
| SCHEMBL6673940 | 0.74 | PTGDR2 (0.40) | PTGDR2SLC6A2SLC6A4NPC1PDE2A | |
| SCHEMBL31393937 | 0.74 | PTGDR2 (0.40) | PTGDR2SLC6A2SLC6A4NPC1PDE2A | |
| SCHEMBL16959297 | 0.72 | GABRA1 (0.42) | PTGDR2SLC6A2SLC6A4NPC1 | |
| SCHEMBL16609146 | 0.70 | PTGDR2 (0.40) | PTGDR2SLC6A2SLC6A4MAPK1HSD17B10 | |
| SCHEMBL24517233 | 0.70 | PTGDR2 (0.37) | PTGDR2SLC6A2SLC6A4ADRB2MAPK1 | |
| SCHEMBL4100718 | 0.70 | MAPK1 (0.41) | PTGDR2ADRB2MAPK1HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022121805-A1 | FUSED RING COMPOUND AS NAV1.8 INHIBITOR AND USE THEREOF | 成都康弘药业集团股份有限公司 | 2022-06-16 | — | — | WO | disclosed |
| CN-114591293-A | Fused ring compound as Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |