Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | FBP1 | P09467 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820714 | 0.97 | — | — | |
| SCHEMBL5033456 | 0.75 | CA12 (0.50) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL818530 | 0.70 | ALDH1A1 (0.38) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL607929 | 0.70 | ALDH1A1 (0.38) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL2754246 | 0.70 | ALDH1A1 (0.38) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL20241415 | 0.69 | ALDH1A1 (0.44) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL37699 | 0.68 | ALDH1A1 (0.55) | CA2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL329111 | 0.68 | ALDH1A1 (0.55) | CA2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL20664588 | 0.68 | ALDH1A1 (0.55) | CA2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL25231611 | 0.68 | ALDH1A1 (0.55) | CA2ALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125862-A1 | PROCESSES FOR THE PREPARATION OF ZANUBRUTINIB AND INTERMEDIATES THEREOF | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2022-06-16 | — | — | WO | disclosed |