SCHEMBL24519133

SCHEMBL24519133

c1ccc(-c2cc3c4ccccc4oc3c3c2[nH]c2ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ MAP3K11 Q16584 3/20 0.43
▸ MAP3K9 P80192 2/20 0.43
▸ CDK5 Q00535 3/20 0.41
▸ DYRK1A Q13627 3/20 0.41
▸ CDK5R1 Q15078 2/20 0.41
▸ MEN1 O00255 4/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ MAPT P10636 3/20 0.40
▸ CSF1R P07333 1/20 0.40
▸ PDGFRB P09619 1/20 0.40
▸ KIT P10721 1/20 0.40
▸ FLT3 P36888 1/20 0.40
▸ HDAC6 Q9UBN7 1/20 0.40
▸ AHR P35869 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ GAA P10253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25681420 0.89 MAP3K11 (0.45) HPGDMAPK1HTTSMN1; SMN2MAP3K11
SCHEMBL27142939 0.87 IDO1 (0.42) MAP3K11MAP3K9CDK5DYRK1ACDK5R1
SCHEMBL25996402 0.83 HPGD (0.47) HPGDMAPK1HTTSMN1; SMN2MAP3K11
SCHEMBL13564021 0.80 AHR (0.47) HPGDMAPK1SMN1; SMN2MEN1KMT2A
SCHEMBL16201582 0.80 MAP3K11 (0.44) MAP3K11MAP3K9CDK5DYRK1ACDK5R1
SCHEMBL30007687 0.80 MAP3K11 (0.44) MAP3K11MAP3K9CDK5DYRK1ACDK5R1
SCHEMBL30019295 0.80 MAP3K11 (0.44) MAP3K11MAP3K9CDK5DYRK1ACDK5R1
SCHEMBL18594338 0.80 AHR (0.54) MAP3K11MAP3K9CDK5DYRK1ACDK5R1
SCHEMBL26365533 0.80 MAP3K11 (0.41) MAP3K11MAP3K9CDK5DYRK1ACDK5R1
SCHEMBL26365531 0.80 HTR2B (0.40) MAP3K11MAP3K9CDK5DYRK1ACDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-08-24 — — US disclosed
EP-4190791-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT Kyulux, Inc. (JP) 2023-06-07 — — EP disclosed
US-11367839-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2022-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT CRY1, CCNE2, CRY2 HPGD 1840/4885MAPK1 4234/4885HTT 854/4885
US-11367839-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof ORAI2, KCNJ2, OR10J3 HPGD 2665/4885MAPK1 1047/4885HTT 4768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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