Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18373946 | 1.00 | ACE (0.54) | ACEACE2OPRD1OPRM1BDKRB2 | |
| SCHEMBL18373945 | 0.99 | ACE (0.55) | ACEACE2OPRD1OPRM1BDKRB2 | |
| SCHEMBL28918903 | 0.99 | ACE (0.55) | ACEACE2OPRD1OPRM1BDKRB2 | |
| SCHEMBL18373913 | 0.99 | ACE (0.55) | ACEACE2OPRD1OPRM1BDKRB2 | |
| SCHEMBL24519195 | 0.99 | ACE (0.55) | ACEACE2OPRD1OPRM1BDKRB2 | |
| SCHEMBL18373947 | 0.99 | ACE (0.55) | ACEACE2OPRD1OPRM1BDKRB2 | |
| SCHEMBL18373953 | 0.99 | ACE (0.55) | ACEACE2OPRD1OPRM1BDKRB2 | |
| SCHEMBL18374215 | 0.97 | ACE (0.51) | ACEACE2OPRD1OPRM1BDKRB2 | |
| SCHEMBL28918703 | 0.97 | ACE (0.57) | ACEACE2OPRD1OPRM1NMUR2 | |
| SCHEMBL21302922 | 0.97 | ACE (0.57) | ACEACE2OPRD1OPRM1NMUR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365215-B2 | Method for preventing, improving, or treating inflammatory bowel disease | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2022-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365215-B2 | Method for preventing, improving, or treating inflammatory bowel disease | SI, NOD2, TNF | ACE 1039/4885ACE2 1532/4885OPRD1 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.