Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21949424 | 0.76 | HRH3 (0.49) | HRH3KDM4EALDH1A1L3MBTL1TACR1 | |
| SCHEMBL12197880 | 0.71 | HRH3 (0.50) | HRH3KDM4EALDH1A1L3MBTL1TACR1 | |
| SCHEMBL20328015 | 0.71 | HRH3 (0.45) | HRH3KDM4EALDH1A1L3MBTL1TACR1 | |
| SCHEMBL13043924 | 0.70 | HRH3 (0.44) | HRH3KDM4EALDH1A1L3MBTL1TACR1 | |
| SCHEMBL23551686 | 0.69 | HRH3 (0.48) | HRH3KDM4EALDH1A1L3MBTL1CYP2D6 | |
| SCHEMBL27881669 | 0.68 | — | — | |
| SCHEMBL18557478 | 0.68 | HRH3 (0.47) | HRH3KDM4EALDH1A1L3MBTL1CYP2D6 | |
| SCHEMBL12339300 | 0.67 | SOS1 (0.33) | — | |
| SCHEMBL23642400 | 0.67 | ALDH1A1 (0.49) | HRH3KDM4EALDH1A1L3MBTL1CYP2D6 | |
| SCHEMBL21017033 | 0.67 | CNR1 (0.40) | HRH3KDM4EALDH1A1L3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365199-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | MERCK PATENT GMBH (DE) | 2022-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365199-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | FSHR, GNRHR, LHCGR | HRH3 945/4885KDM4E 2303/4885ALDH1A1 4610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.