SCHEMBL2452017

SCHEMBL2452017

COc1ccc(C=Nc2ccc(N=Nc3ccccc3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.66
PTGS2 P35354 2/20 0.57
CA2 P00918 2/20 0.57
PTGS1 P23219 1/20 0.57
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
ALDH1A1 P00352 7/20 0.55
GAA P10253 6/20 0.55
KDM4E B2RXH2 4/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
GLA P06280 1/20 0.51
TRPA1 O75762 1/20 0.50
MAPT P10636 7/20 0.49
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.49
PKM P14618 2/20 0.49
THRB P10828 1/20 0.49
CASP3 P42574 1/20 0.49
RECQL P46063 1/20 0.49
BLM P54132 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5718585 1.00 S100B (0.66) S100BPTGS2CA2PTGS1CA12
SCHEMBL12416624 1.00 S100B (0.66) S100BPTGS2CA2PTGS1CA12
SCHEMBL443413 0.93 S100B (0.69) S100BPTGS2CA2PTGS1CA12
SCHEMBL443412 0.93 S100B (0.69) S100BPTGS2CA2PTGS1CA12
SCHEMBL3131079 0.90 S100B (0.69) S100BPTGS2CA2PTGS1CA12
SCHEMBL3131073 0.90 S100B (0.69) S100BPTGS2CA2PTGS1CA12
SCHEMBL10733285 0.88 S100B (0.82) S100BPTGS2CA2PTGS1CA12
SCHEMBL12416630 0.88 S100B (0.82) S100BPTGS2CA2PTGS1CA12
SCHEMBL10412841 0.88 S100B (0.82) S100BPTGS2CA2PTGS1CA12
SCHEMBL10733277 0.88 S100B (0.82) S100BPTGS2CA2PTGS1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5169678-A Rendering at specific laser frequency by mixing ultraviolet wavelength absorpted azo dyes with thermoplastic resins GENERAL ELECTRIC COMPANY (US) 1992-12-08 US claimed
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 WO disclosed
US-5169678-A Rendering at specific laser frequency by mixing ultraviolet wavelength absorpted azo dyes with thermoplastic resins GENERAL ELECTRIC COMPANY (US) 1992-12-08 US disclosed
US-5146303-A Compact, thermally efficient focal plane array and testing and repair thereof GENERAL ELECTRIC COMPANY (US) 1992-09-08 US disclosed
EP-0436320-A2 Laser ablatable polymer dielectrics and methods GENERAL ELECTRIC COMPANY (US) 1991-07-10 EP disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-4038200-A LYOTROPIC NEMATIC LIQUID CRYSTALS FOR USE IN ELECTRO-OPTICAL DISPLAY DEVICES TEXAS INSTRUMENTS INCORPORATED (US) 1977-07-26 US disclosed
US-4038199-A LYOTROPIC NEMATIC LIQUID CRYSTALS FOR USE IN ELECTRO-OPTICAL DISPLAY DEVICES TEXAS INSTRUMENTS INCORPORATED (US) 1977-07-26 US disclosed
US-4005928-A Nematic liquid crystal displays for low voltage direct current operation TEXAS INSTRUMENTS INCORPORATED (US) 1977-02-01 US disclosed
US-3957346-A Method for altering elliptically polarized light XEROX CORPORATION (US) 1976-05-18 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed