SCHEMBL443412

SCHEMBL443412

COc1ccc(/C=N/c2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.69
PTGS2 P35354 3/20 0.59
PTGS1 P23219 2/20 0.59
CA2 P00918 2/20 0.59
CA12 O43570 1/20 0.59
CA9 Q16790 1/20 0.59
ALDH1A1 P00352 6/20 0.58
L3MBTL1 Q9Y468 3/20 0.58
KDM4E B2RXH2 3/20 0.58
GLA P06280 1/20 0.58
TRPA1 O75762 1/20 0.57
GAA P10253 4/20 0.56
G6PC1 P35575 1/20 0.53
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
CA1 P00915 1/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
PKM P14618 1/20 0.50
CASP3 P42574 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443413 1.00 S100B (0.69) S100BPTGS2PTGS1CA2CA12
SCHEMBL12416624 0.93 S100B (0.66) S100BPTGS2PTGS1CA2CA12
SCHEMBL5718585 0.93 S100B (0.66) S100BPTGS2PTGS1CA2CA12
SCHEMBL2452017 0.93 S100B (0.66) S100BPTGS2PTGS1CA2CA12
SCHEMBL3131079 0.92 S100B (0.69) S100BPTGS2PTGS1CA2CA12
SCHEMBL3131073 0.92 S100B (0.69) S100BPTGS2PTGS1CA2CA12
SCHEMBL10733285 0.90 S100B (0.82) S100BPTGS2PTGS1CA2CA12
SCHEMBL10412841 0.90 S100B (0.82) S100BPTGS2PTGS1CA2CA12
SCHEMBL12416630 0.90 S100B (0.82) S100BPTGS2PTGS1CA2CA12
SCHEMBL10733277 0.90 S100B (0.82) S100BPTGS2PTGS1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024255129-A1 RECYCLABLE EPOXY RESIN, SYSTEM MATERIAL AND COMPOSITE MATERIAL THEREOF, AND RECOVERY METHODS THEREFOR 道生天合材料科技(上海)股份有限公司 2024-12-19 WO claimed
US-20120065430-A1 Application of Metal Amidoborane and Their Derivatives in Reduction Reaction DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2012-03-15 US claimed
CN-119303575-A Novel Cu+Zr (OH)4Application of physical mixed catalyst in catalytic synthesis of N-benzylidene aniline or derivative thereof 兰州大学 2025-01-14 CN disclosed
WO-2024255129-A1 RECYCLABLE EPOXY RESIN, SYSTEM MATERIAL AND COMPOSITE MATERIAL THEREOF, AND RECOVERY METHODS THEREFOR 道生天合材料科技(上海)股份有限公司 2024-12-19 WO disclosed
EP-3469576-B1 MULTI-LAYER DISPLAY WITH COLOR AND CONTRAST ENHANCEMENT SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-03 EP disclosed
US-11891408-B2 Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane SOOCHOW UNIVERSITY (CN) 2024-02-06 US disclosed
US-20220008887-A1 Swellable Organically Modified Silica as Nanoreactors APPALACHIAN STATE UNIVERSITY 2022-01-13 US disclosed
US-20210221828-A1 APPLICATION OF LITHIUM 4-METHOXYANILINE IN CATALYSIS OF HYDROBORATION REACTION OF IMINE AND BORANE SOOCHOW UNIVERSITY (CN) 2021-07-22 US disclosed
US-10953393-B2 Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations THE UNIVERSITY OF CHICAGO (US) 2021-03-23 US disclosed
US-10953393-B2 Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations THE UNIVERSITY OF CHICAGO (US) 2021-03-23 US disclosed
US-10565925-B2 Full color display with intrinsic transparency SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-02-18 US disclosed
US-4224340-A Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds WILLIAM H. RORER, INC. (US) 1980-09-23 US disclosed
US-4214003-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1980-07-22 US disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 US disclosed
US-4012434-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-03-15 US disclosed
US-4002670-A 4'-ALKOXY OR ALKYL PHENYL ESTERS OF 4-ALKYL OR ALKOXY BENZOIC ACIDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-11 US disclosed
US-4001137-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US disclosed
US-3993645-A Stilbene optical brighteners and compositions brightened therewith STERLING DRUG INC. (US) 1976-11-23 US disclosed
US-3932301-A NYLON, POLYESTERS STERLING DRUG INC. (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10953393-B2 Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations SBK1, SIK1, SIK2 S100B 4289/4885PTGS2 1157/4885PTGS1 2882/4885
US-20220008887-A1 Swellable Organically Modified Silica as Nanoreactors MSN, SORD, OGA S100B 685/4885PTGS2 3420/4885PTGS1 3300/4885
US-20210221828-A1 APPLICATION OF LITHIUM 4-METHOXYANILINE IN CATALYSIS OF HYDROBORATION REACTION OF IMINE AND BORANE ME1, MCM4, INMT S100B 3840/4885PTGS2 1462/4885PTGS1 1684/4885
US-11891408-B2 Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane ME1, MCM4, INMT S100B 3840/4885PTGS2 1462/4885PTGS1 1684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.