Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854448 | 0.85 | POLB (0.92) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL3338581 | 0.83 | F2 (0.61) | POLBNPC1RAB9ALMNACYP1A2 | |
| SCHEMBL7006523 | 0.82 | POLB (1.00) | POLBNPC1RAB9ACYP2D6CYP2C19 | |
| SCHEMBL30701863 | 0.80 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL30701864 | 0.80 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL2331252 | 0.80 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL7854826 | 0.80 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL7856315 | 0.80 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL7856311 | 0.80 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL27492580 | 0.80 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015044-A1 | METHOD FOR PREPARING ENANTIOMER OF SULFOXIDE COMPOUND, AND SYSTEM FOR PREPARING ENANTIOMER | Tokyo University of Science Foundation (JP) | 2022-06-22 | — | — | EP | disclosed |