SCHEMBL24521041

SCHEMBL24521041

N#Cc1cccc2c1-c1cc(-c3cccc(-c4cc(-c5ccccc5)nc(-c5ccccc5)n4)c3)c3ccccc3c1C2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.39
HPGD P15428 5/20 0.36
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
ALDH1A1 P00352 5/20 0.36
KDM4E B2RXH2 4/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 3/20 0.36
GLA P06280 1/20 0.36
SQOR Q9Y6N5 2/20 0.36
ABCG2 Q9UNQ0 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
GBA1 P04062 1/20 0.35
NTSR1 P30989 1/20 0.35
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
ADORA2A P29274 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24521214 0.88 KCNH2 (0.43) KCNH2MEN1KMT2AALDH1A1LMNA
SCHEMBL24521134 0.87 KCNH2 (0.41) KCNH2MEN1KMT2AALDH1A1KDM4E
SCHEMBL24521105 0.86 MEN1 (0.39) HPGDMEN1KMT2AALDH1A1KDM4E
SCHEMBL24521125 0.86 ABCG2 (0.40) HPGDMEN1KMT2AALDH1A1KDM4E
SCHEMBL24521132 0.86 KCNH2 (0.42) KCNH2HPGDMEN1KMT2AALDH1A1
SCHEMBL24521101 0.85 MEN1 (0.39) HPGDMEN1KMT2AALDH1A1KDM4E
SCHEMBL24521007 0.84 ABCG2 (0.40) HPGDMEN1KMT2AALDH1A1KDM4E
SCHEMBL25774511 0.79 GABRG2 (0.45) HPGDMEN1KMT2AALDH1A1KDM4E
SCHEMBL24521004 0.78 CYP1A2 (0.38) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL24521098 0.77 CYP1A1 (0.42) HPGDMEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015515-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2022-06-22 EP disclosed