SCHEMBL24521101

SCHEMBL24521101

c1ccc(-c2cc(-c3cccc(-c4cccc(-c5cc6c(c7ccccc57)Cc5cccc(-c7ccccc7)c5-6)c4)c3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
LMNA P02545 3/20 0.39
KDM4E B2RXH2 2/20 0.39
GLA P06280 1/20 0.39
NTSR1 P30989 1/20 0.37
THRB P10828 1/20 0.36
ADORA2A P29274 3/20 0.35
ADORA1 P30542 3/20 0.35
ACACA Q13085 2/20 0.35
EGFR P00533 1/20 0.34
MAOB P27338 3/20 0.33
MAOA P21397 2/20 0.33
ACHE P22303 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24521105 0.99 MEN1 (0.39) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24521092 0.92 ADORA2A (0.37) MAPTALDH1A1HPGDKDM4EADORA2A
SCHEMBL24521123 0.92 ALDH1A1 (0.39) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24521125 0.91 ABCG2 (0.40) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24521098 0.89 CYP1A1 (0.42) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24521007 0.89 ABCG2 (0.40) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24521159 0.87 MAPT (0.35) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24521041 0.85 KCNH2 (0.39) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24521273 0.85 MEN1 (0.40) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24521290 0.84 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015515-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2022-06-22 EP disclosed