SCHEMBL24521252

SCHEMBL24521252

Brc1ccc2c(c1)-c1ccccc1C1C=CC=CC21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
MAPK1 P28482 1/20 0.50
EDNRB P24530 2/20 0.42
EDNRA P25101 2/20 0.42
PTPRC P08575 1/20 0.40
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
HTR2A P28223 2/20 0.35
HTR2C P28335 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CYP2A6 P11509 1/20 0.33
AR P10275 1/20 0.33
S100A4 P26447 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564590 0.80 CYP1A2 (0.72) CYP1A2MAPK1EDNRBEDNRAPTPRC
SCHEMBL30713645 0.77 CYP1A2 (0.53) CYP1A2MAPK1EDNRBEDNRAPTPRC
SCHEMBL21888240 0.77 MAPK1 (0.53) CYP1A2MAPK1EDNRBEDNRAPTPRC
SCHEMBL20082694 0.77 CYP1A2 (0.53) CYP1A2MAPK1EDNRBEDNRAPTPRC
SCHEMBL26119454 0.77 MAPK1 (0.53) CYP1A2MAPK1EDNRBEDNRAPTPRC
SCHEMBL5829696 0.76 ALDH1A1 (0.38) MAPK1HTR2AMEN1KMT2ASCN1A
SCHEMBL10042990 0.74 CYP1A2 (0.50) CYP1A2MAPK1EDNRBEDNRAPTPRC
SCHEMBL19785704 0.74 CYP1A2 (0.38) CYP1A2MAPK1EDNRBEDNRA
SCHEMBL30713690 0.73 CYP1A2 (0.49) CYP1A2MAPK1EDNRBEDNRAPTPRC
SCHEMBL27716951 0.73 CYP1A2 (0.53) CYP1A2MAPK1EDNRBEDNRAPTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4265612-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT Materials Co., Ltd. (KR) 2023-10-25 EP disclosed
EP-4015515-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2022-06-22 EP disclosed