SCHEMBL5829696

SCHEMBL5829696

C1=CC2c3ccccc3-c3cc4ccccc4cc3C2C=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TP53 P04637 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HIF1A Q16665 1/20 0.38
PPIA P62937 1/20 0.37
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GPR3 P46089 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24123358 0.79 GSTP1 (0.33) ALDH1A1TP53HSD17B10HPGDTSHR
SCHEMBL24521252 0.76 CYP1A2 (0.50) MAPK1MEN1KMT2AGPR3HTR2A
SCHEMBL17230349 0.72 ALDH1A1 (0.56) ALDH1A1TP53HSD17B10HPGDTSHR
SCHEMBL25719034 0.72 HTR7 (0.43) ALDH1A1TP53HSD17B10HPGDTSHR
SCHEMBL8205238 0.72 ALDH1A1 (0.43) ALDH1A1TP53HSD17B10HPGDTSHR
SCHEMBL17792652 0.71 MEN1 (0.32) ALDH1A1TP53HSD17B10HPGDKDM4E
SCHEMBL24772137 0.71 MEN1 (0.38) ALDH1A1HPGDTSHRMAPK1KDM4E
SCHEMBL24061491 0.70 ESR1 (0.36) ALDH1A1TP53HSD17B10HPGDTSHR
SCHEMBL22505151 0.70 MEN1 (0.37) ALDH1A1HPGDTSHRKDM4EMEN1
SCHEMBL16168528 0.69 MEN1 (0.43) ALDH1A1TP53MAPK1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333554-B1 THERMAL-TREATMENT PROCESS OF HYDROCARBON FEEDS IN THE PRESENCE OF POLYSULFIDES AND HYDROGEN DONORS Institut Français du Pétrole (FR) 1992-09-02 EP claimed
EP-0333554-A1 Thermal-treatment process of hydrocarbon feeds in the presence of polysulfides and hydrogen donors Institut Français du Pétrole (FR) 1989-09-20 EP claimed
US-7119206-B2 Derivative of dihydro-dibenzo (a) anthracenes and their use as selective estrogen receptor modulators ELI LILLY AND COMPANY (US) 2006-10-10 US disclosed
US-20060122386-A1 Derivative of dihydro-dibenzo (a) anthracenes and their use as selective estrogen receptor modulators ELI LILLY AND COMPANY 2006-06-08 US disclosed
EP-1546139-A1 DERIVATIVE OF DIHYDRO-DIBENZO (A) ANTHRACENES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-06-29 EP disclosed
WO-2004029047-A1 DERIVATIVE OF DIHYDRO-DIBENZO (A) ANTHRACENES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2004-04-08 WO disclosed
EP-0333554-B1 THERMAL-TREATMENT PROCESS OF HYDROCARBON FEEDS IN THE PRESENCE OF POLYSULFIDES AND HYDROGEN DONORS Institut Français du Pétrole (FR) 1992-09-02 EP disclosed
EP-0333554-A1 Thermal-treatment process of hydrocarbon feeds in the presence of polysulfides and hydrogen donors Institut Français du Pétrole (FR) 1989-09-20 EP disclosed
EP-0063052-B1 STARTING PITCHES FOR CARBON FIBERS NIPPON OIL CO. LTD. (JP) 1986-09-03 EP disclosed
EP-0063053-B1 STARTING PITCHES FOR CARBON FIBERS NIPPON OIL CO. LTD. (JP) 1986-03-12 EP disclosed
US-4521294-A Starting pitches for carbon fibers NIPPON OIL CO., LTD. (JP) 1985-06-04 US disclosed
US-4397830-A HEAT TREATMENT OF HEAVY OIL AND HYDROGENATED HEAVY OIL NIPPON OIL CO., LTD. (JP) 1983-08-09 US disclosed
EP-0063053-A2 Starting pitches for carbon fibers NIPPON OIL CO. LTD. (JP) 1982-10-20 EP disclosed
EP-0063052-A2 Starting pitches for carbon fibers NIPPON OIL CO. LTD. (JP) 1982-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122386-A1 Derivative of dihydro-dibenzo (a) anthracenes and their use as selective estrogen receptor modulators ESR1, GPER1, ESR2 ALDH1A1 1604/4885TP53 370/4885HSD17B10 376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.