Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | WNT3 | P56703 | 1/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909244 | 0.83 | EPHX2 (0.49) | KMT2AALDH1A1SMN1; SMN2ATMEPHX2 | |
| SCHEMBL21281206 | 0.83 | NPC1 (0.41) | KMT2AALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL19444620 | 0.82 | KMT2A (0.47) | KMT2AALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL19444608 | 0.82 | KMT2A (0.47) | KMT2AALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL24521422 | 0.82 | CPN1 (0.40) | KMT2AALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL21281128 | 0.80 | EPHX2 (0.49) | KMT2AALDH1A1SMN1; SMN2LMNAEPHX2 | |
| SCHEMBL30098883 | 0.80 | LMNA (0.41) | KMT2AALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL22030873 | 0.79 | CYP3A4 (0.41) | KMT2AALDH1A1SMN1; SMN2LMNAATM | |
| SCHEMBL24244796 | 0.79 | CPN1 (0.40) | KMT2AALDH1A1SMN1; SMN2LMNADPP4 | |
| SCHEMBL1226363 | 0.79 | ATM (0.50) | KMT2AALDH1A1SMN1; SMN2ATMDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596072-B1 | PYRAZOLOCHLOROPHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2022-06-22 | — | — | EP | disclosed |