SCHEMBL24521559

SCHEMBL24521559

N[C@@H](Cc1cnc[nH]1)C(=O)NCc1ccccc1C(F)(F)F

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NLN Q9BYT8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21794928 0.79 NLN (0.66) NLN
SCHEMBL24521558 0.79 MEN1 (0.54)
SCHEMBL23572998 0.78 EPHX2 (0.41)
SCHEMBL21794929 0.78 EPHX2 (0.41)
SCHEMBL23573003 0.78 EPHX2 (0.41)
SCHEMBL8819734 0.76 MEN1 (0.62) NLN
SCHEMBL8819723 0.76 MEN1 (0.62) NLN
SCHEMBL24521552 0.76 EPHX2 (0.53)
SCHEMBL24521506 0.76 EPHX2 (0.53)
SCHEMBL27776881 0.74 NLN (0.79) NLN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015501-A1 N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS Consejo Superior de Investigaciones Científicas (CSIC) (ES) 2022-06-22 EP disclosed