Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521559 | 0.79 | NLN (0.60) | — | |
| SCHEMBL2741584 | 0.78 | TAAR1 (0.54) | CYP3A4CYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL24521563 | 0.77 | KMT2A (0.54) | MEN1KMT2ALMNAEPHX2 | |
| SCHEMBL24521575 | 0.75 | MEN1 (0.47) | MEN1KMT2ACYP2D6CYP2C19EPHX2 | |
| SCHEMBL24521564 | 0.75 | MEN1 (0.47) | MEN1KMT2ACYP2D6CYP2C19EPHX2 | |
| SCHEMBL7849085 | 0.74 | MEN1 (0.87) | MEN1KMT2ALMNARECQLTRPV1 | |
| SCHEMBL27858969 | 0.74 | EPHX2 (0.62) | MEN1KMT2AEPHX2 | |
| SCHEMBL24521599 | 0.74 | MEN1 (0.59) | MEN1KMT2ACYP3A4CYP2C19EPHX2 | |
| SCHEMBL24521507 | 0.74 | EPHX2 (0.62) | MEN1KMT2AEPHX2TRPV1 | |
| SCHEMBL6981160 | 0.73 | PTGES (0.49) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |