Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521506 | 1.00 | EPHX2 (0.53) | EPHX2PPARGOPRK1 | |
| SCHEMBL29052274 | 0.80 | MTOR (0.58) | EPHX2PPARG | |
| SCHEMBL24521505 | 0.80 | MTOR (0.58) | EPHX2PPARG | |
| SCHEMBL24521567 | 0.77 | CTSS (0.61) | — | |
| SCHEMBL29052268 | 0.77 | CTSS (0.61) | — | |
| SCHEMBL27134423 | 0.77 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL24521555 | 0.77 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL27150973 | 0.77 | MMP2 (0.51) | EPHX2PPARG | |
| SCHEMBL24521509 | 0.77 | MMP2 (0.51) | EPHX2PPARG | |
| SCHEMBL24521507 | 0.76 | EPHX2 (0.62) | EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583497-A | N-benzyl-alpha-aminoamides as late promoting complex/loop (APC/C) inhibitors | 科学研究高级委员会(CSIC) | 2023-08-11 | — | — | CN | disclosed |
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |