Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795143 | 0.80 | SMN1; SMN2 (0.47) | KMT2AMEN1GAALMNAP2RX7 | |
| SCHEMBL21794929 | 0.79 | EPHX2 (0.41) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL23572998 | 0.79 | EPHX2 (0.41) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL23573003 | 0.79 | EPHX2 (0.41) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL222959 | 0.78 | DAO (0.43) | POLBHDAC1ATM | |
| SCHEMBL24521558 | 0.77 | MEN1 (0.54) | KMT2AMEN1EPHX2LMNA | |
| SCHEMBL7849085 | 0.74 | MEN1 (0.87) | KMT2AMEN1POLBGAALMNA | |
| SCHEMBL24521599 | 0.74 | MEN1 (0.59) | KMT2AMEN1EPHX2TAOK1TAOK3 | |
| SCHEMBL27858969 | 0.74 | EPHX2 (0.62) | KMT2AMEN1EPHX2POLBGAA | |
| SCHEMBL24521507 | 0.74 | EPHX2 (0.62) | KMT2AMEN1EPHX2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |