Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380317 | 0.84 | LMNA (0.59) | LMNAPOLBEPHX2PPARGTDP1 | |
| SCHEMBL9118035 | 0.84 | CYP3A4 (0.60) | CYP3A4CA1CA2BCHECHRM2 | |
| SCHEMBL24528566 | 0.83 | MEN1 (0.56) | MEN1KMT2AEPHX2BCHECHRM2 | |
| SCHEMBL14102774 | 0.81 | CYP3A4 (0.75) | CYP3A4MEN1KMT2ACA1CA2 | |
| SCHEMBL4708018 | 0.81 | LMNA (0.53) | MEN1KMT2ALMNAPOLBEPHX2 | |
| SCHEMBL24521597 | 0.81 | LMNA (0.47) | CYP3A4MEN1KMT2ACA1CA2 | |
| SCHEMBL24528572 | 0.80 | CA1 (0.52) | CYP3A4CA1CA2LMNAPOLB | |
| SCHEMBL29052300 | 0.80 | CA1 (0.52) | CYP3A4CA1CA2LMNAPOLB | |
| SCHEMBL9116823 | 0.79 | CYP3A4 (0.54) | CYP3A4CA1CA2EPHX2BCHE | |
| SCHEMBL16269072 | 0.78 | KMT2A (0.58) | CYP3A4MEN1KMT2AEPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |