Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052300 | 0.87 | CA1 (0.52) | LMNAPOLBCA1CA2SCN9A | |
| SCHEMBL24528572 | 0.87 | CA1 (0.52) | LMNAPOLBCA1CA2SCN9A | |
| SCHEMBL24521509 | 0.81 | MMP2 (0.51) | MEN1KMT2AEPHX2PPARG | |
| SCHEMBL27150973 | 0.81 | MMP2 (0.51) | MEN1KMT2AEPHX2PPARG | |
| SCHEMBL24521598 | 0.81 | CYP3A4 (0.58) | LMNAPOLBCA1CA2CYP3A4 | |
| SCHEMBL20380317 | 0.81 | LMNA (0.59) | LMNAPOLBKCNA5EPHX2PPARG | |
| SCHEMBL2931394 | 0.79 | MEN1 (0.52) | CA1CA2CYP3A4MEN1GAA | |
| SCHEMBL3800689 | 0.78 | ANPEP (0.50) | CA1CA2CYP3A4MEN1GAA | |
| SCHEMBL3800686 | 0.78 | ANPEP (0.50) | CA1CA2CYP3A4MEN1GAA | |
| SCHEMBL4708018 | 0.78 | LMNA (0.53) | LMNAPOLBKCNA5SCN9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |