Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877953 | 0.94 | CA14 (0.55) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL13055403 | 0.93 | CA14 (0.54) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL16917201 | 0.92 | CA12 (0.45) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL13055414 | 0.92 | CA14 (0.53) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL13055411 | 0.92 | CA14 (0.53) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL13055399 | 0.92 | CA14 (0.53) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL18950461 | 0.89 | CA14 (0.63) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL13055580 | 0.89 | TDP1 (0.47) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL14877954 | 0.88 | CA14 (0.58) | CA14CA12CA1CA7TDP1 | |
| SCHEMBL14877951 | 0.88 | CA14 (0.58) | CA14CA12CA1CA7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383846-B1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | OTAGO INNOVATION LTD (NZ) | 2022-06-22 | — | — | EP | disclosed |