SCHEMBL24521732

SCHEMBL24521732

CC1=C(c2ccccc2N)C(C)CC(C(C)(C)C)=C1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
ACHE P22303 2/20 0.33
S1PR1 P21453 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14418022 0.69 MAPK1 (0.31) ALDH1A1
SCHEMBL78463 0.66 ACHE (0.40) ALDH1A1L3MBTL1NOS3NOS2ACHE
SCHEMBL8786691 0.63 ALDH1A1 (0.39) ALDH1A1L3MBTL1NOS2HSD17B10MEN1
Methyl Alcohol SCHEMBL28248582 0.60 ALDH1A1 (0.81) ALDH1A1L3MBTL1HSD17B10MEN1GAA
SCHEMBL22562268 0.59 ALDH1A1 (0.39) ALDH1A1L3MBTL1NOS3NOS2HSD17B10
SCHEMBL5952877 0.59 ACHE (0.60) ALDH1A1L3MBTL1ACHEHSD17B10MEN1
SCHEMBL23105552 0.58 ALDH1A1 (0.59) ALDH1A1L3MBTL1S1PR1HSD17B10MEN1
SCHEMBL25052987 0.58
SCHEMBL24084843 0.57
SCHEMBL27470486 0.57 ALDH1A1 (0.56) ALDH1A1L3MBTL1S1PR1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4016656-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2022-06-22 EP disclosed