Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.51 |
| ▸ | ITGB6 | P18564 | 15/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 14/20 | 0.51 |
| ▸ | ITGB8 | P26012 | 13/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20153336 | 0.79 | ITGB3 (0.64) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24521902 | 0.78 | ITGB3 (0.61) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24521899 | 0.78 | ITGB3 (0.67) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24521881 | 0.77 | ITGB3 (0.56) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL23542430 | 0.71 | ITGAV (0.61) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL6262063 | 0.71 | ITGB3 (0.74) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL10051072 | 0.70 | ITGAV (0.68) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24521988 | 0.70 | ITGB3 (0.63) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| Hydrochloric Acid SCHEMBL6424214 | 0.70 | ITGB3 (0.72) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| Hydrochloric Acid SCHEMBL29416400 | 0.70 | ITGB3 (0.72) | ITGAVITGB3ITGB6ITGB5ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |