Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.63 |
| ▸ | ITGAV | P06756 | 20/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | ITGB5 | P18084 | 12/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.50 |
| ▸ | ITGB8 | P26012 | 11/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262063 | 0.82 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| Hydrochloric Acid SCHEMBL29416400 | 0.81 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| Hydrochloric Acid SCHEMBL6424214 | 0.81 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL20156036 | 0.81 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL20153337 | 0.80 | ITGAV (0.51) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL24521901 | 0.79 | ITGAV (0.54) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL15397316 | 0.79 | ITGB3 (0.79) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL20153504 | 0.78 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL24521992 | 0.78 | ITGB3 (0.52) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| Hydrochloric Acid SCHEMBL20487381 | 0.78 | ITGB3 (0.77) | ITGB3ITGAVITGA2BITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |