SCHEMBL2452193

SCHEMBL2452193

C[Si](C)(Cl)CCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149083 0.79 ALDH1A1 (0.46)
SCHEMBL159716 0.79
SCHEMBL17966474 0.77
SCHEMBL2103848 0.77
SCHEMBL6359432 0.76
SCHEMBL8837730 0.76
SCHEMBL2329675 0.76
SCHEMBL4530934 0.74 TSHR (0.43)
SCHEMBL4534717 0.74 TSHR (0.43)
SCHEMBL8756007 0.74 TSHR (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143800-A Silicon-based phosphate, composition and catalyst for synthesizing polyketone 黄河三角洲京博化工研究院有限公司 2024-12-17 CN disclosed
EP-4186915-A1 METHOD FOR SYNTHESIZING C-NUCLEOSIDE COMPOUND Sichuan University (CN) 2023-05-31 EP disclosed
US-20170145136-A1 RESIN COMPOSITION FOR GOLF BALL AND GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2017-05-25 US disclosed
WO-2017067877-A1 AMINOSILANE-FUNCTIONALIZED DIENES FOR USE IN FUNCTIONALIZATION OF ELASTOMERIC POLYMERS TRINSEO EUROPE GMBH (CH) 2017-04-27 WO disclosed
US-9598522-B2 Resin composition for golf ball and golf ball DUNLOP SPORTS CO. LTD. (JP) 2017-03-21 US disclosed
US-20150183916-A1 RESIN COMPOSITION FOR GOLF BALL AND GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2015-07-02 US disclosed
EP-1963340-B1 METHOD FOR THE PRODUCTION OF (MERCAPTOORGANYL)ALKYL POLYETHER SILANES EVONIK DEGUSSA GMBH (DE) 2011-09-14 EP disclosed
US-7799938-B2 Method for the production of (mercaptoorganyl)alkyl polyether silanes EVONIK DEGUSSA GMBH (DE) 2010-09-21 US disclosed
CN-100520608-C Toner CANON KK (JP) 2009-07-29 CN disclosed
CN-101472959-A Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECH HOLDINGS CV (NL) 2009-07-01 CN disclosed
US-4977255-A Steroidal 17α-silyl ethers and process to corticoids and progesterones THE UPJOHN COMPANY (US) 1990-12-11 US disclosed
US-4921638-A 17β-cyano-9α,17α-dihydroxyandrost-4-en-3-one THE UPJOHN COMPANY (US) 1990-05-01 US disclosed
EP-0334875-A1 STEROIDAL 17$g(a)-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES THE UPJOHN COMPANY (US) 1989-10-04 EP disclosed
EP-0268400-A1 Steroidal 17alpha-silyl ethers and process to corticoids and progesterones THE UPJOHN COMPANY (US) 1988-05-25 EP disclosed
WO-1988003534-A1 STEROIDAL 17alpha-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES THE UPJOHN COMPANY (US) 1988-05-19 WO disclosed
EP-0110258-B1 A METHOD FOR THE PREPARATION OF A POLYVINYL CHLORIDE RESIN SHAPED ARTICLE WITH METALLIZED SURFACE Shin-Etsu Chemical Co., Ltd. (JP) 1987-04-22 EP disclosed
US-4639379-A PLASMA POLYMERIZATION OF SILANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1987-01-27 US disclosed
US-4603057-A Method for the preparation of a polyvinyl chloride resin shaped article with metallized surface SHIN-ETSU CHEMICAL CO., LTD. (JP) 1986-07-29 US disclosed
EP-0110258-A1 A method for the preparation of a polyvinyl chloride resin shaped article with metallized surface Shin-Etsu Chemical Co., Ltd. (JP) 1984-06-13 EP disclosed
US-4053497-A B-HALOGENOETHYL SILANE CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed