Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205330 | 0.89 | KDM4E (0.38) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL24519957 | 0.88 | KDM4E (0.36) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL21794418 | 0.86 | AHR (0.42) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL22389063 | 0.85 | ALK (0.35) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL21790982 | 0.82 | ALDH1A1 (0.37) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL22388853 | 0.82 | ALK (0.33) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL22388866 | 0.82 | ALK (0.33) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL22389077 | 0.82 | ALK (0.35) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL24524171 | 0.81 | KMT2A (0.58) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL20205558 | 0.81 | PGR (0.44) | KMT2ARAB9AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3844242-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-22 | — | — | EP | disclosed |