SCHEMBL24522091

SCHEMBL24522091

Nc1cc(C23CC4CC(CC(C4)C2)C3)cc(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
LMNA P02545 5/20 0.63
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
GAA P10253 2/20 0.47
POLB P06746 1/20 0.47
GFER P55789 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.40
EPHX2 P34913 2/20 0.39
PGR P06401 1/20 0.39
MAPT P10636 3/20 0.38
USP2 O75604 1/20 0.38
THRB P10828 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
RAB9A P51151 1/20 0.38
NPC1 O15118 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21039142 0.79 ALDH1A1 (0.60) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL27584489 0.77 LMNA (0.52) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL399431 0.77 ALDH1A1 (1.00) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL548788 0.77 MEN1 (0.57) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL11021413 0.77 ALDH1A1 (0.52) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL21307949 0.77 ALDH1A1 (0.52) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL28728268 0.77 ALDH1A1 (0.52) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL28727976 0.77 ALDH1A1 (0.52) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL23039206 0.77 LMNA (0.67) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL17358864 0.76 MEN1 (0.46) ALDH1A1LMNAMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4016659-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-06-22 EP disclosed