Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333484 | 0.88 | GPR119 (0.75) | GPR119 | |
| SCHEMBL2450210 | 0.85 | GPR119 (0.78) | GPR119 | |
| SCHEMBL12333726 | 0.84 | GPR119 (0.53) | GPR119PIK3CDPIK3CA | |
| SCHEMBL2457902 | 0.83 | GPR119 (0.52) | GPR119 | |
| SCHEMBL2454369 | 0.81 | GPR119 (0.78) | GPR119 | |
| SCHEMBL2454874 | 0.80 | GPR119 (0.66) | GPR119 | |
| SCHEMBL2453004 | 0.79 | GPR119 (0.52) | GPR119 | |
| SCHEMBL2334427 | 0.79 | GPR119 (0.81) | GPR119 | |
| SCHEMBL2456600 | 0.79 | GPR119 (0.58) | GPR119 | |
| SCHEMBL2455221 | 0.79 | GPR119 (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170864-B1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-14 | — | — | EP | claimed |