SCHEMBL2457902

SCHEMBL2457902

Cc1nc(S(C)(=O)=O)ccc1-n1ccc(OC2CCN(C(=O)O)CC2)cc1=O

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2338227 0.88 GPR119 (0.68) GPR119
SCHEMBL2453875 0.84 GPR119 (0.44) GPR119
SCHEMBL12333861 0.84 GPR119 (0.45) GPR119
SCHEMBL4320329 0.84 GPR119 (0.55) GPR119
SCHEMBL2452229 0.83 GPR119 (0.58) GPR119
SCHEMBL2455244 0.80 GPR119 (0.63) GPR119
SCHEMBL2454314 0.80 GPR119 (0.60) GPR119
SCHEMBL2450210 0.79 GPR119 (0.78) GPR119
SCHEMBL2334961 0.79 GPR119 (0.72) GPR119
SCHEMBL2454874 0.77 GPR119 (0.66) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2170864-B1 PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2011-09-14 EP claimed