Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24522478 | 0.89 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL24522581 | 0.82 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL17001569 | 0.78 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL24522418 | 0.77 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL24522408 | 0.77 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL19935149 | 0.76 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL24522398 | 0.76 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL19935231 | 0.75 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL19934952 | 0.75 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL24522496 | 0.74 | P2RX7 (0.36) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129365-A1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | AXXAM S.P.A. (IT) | 2022-06-23 | — | — | WO | disclosed |
| EP-4015039-A1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | AXXAM S.p.A. (IT) | 2022-06-22 | — | — | EP | disclosed |