Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959771 | 0.76 | MAPT (0.60) | KDRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23959796 | 0.76 | HDAC6 (0.53) | KDRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23959786 | 0.73 | CYP1A2 (0.52) | KDRMEN1KMT2AL3MBTL1HTT | |
| SCHEMBL11262478 | 0.71 | KDM4E (0.69) | KDRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL30511903 | 0.71 | KDM4E (0.69) | KDRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23959781 | 0.69 | KDR (0.71) | KDRRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL17486864 | 0.69 | KDR (0.70) | KDRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL22041544 | 0.69 | TDP1 (0.69) | KDRMEN1KMT2AHTTKDM4E | |
| SCHEMBL29763591 | 0.69 | TDP1 (0.69) | KDRMEN1KMT2AHTTKDM4E | |
| SCHEMBL22072823 | 0.68 | TDP1 (0.58) | KDRRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |