Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29763591 | 1.00 | TDP1 (0.69) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL28343328 | 0.87 | POLB (0.69) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL28340849 | 0.87 | POLB (0.68) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL1753903 | 0.86 | TDP1 (0.79) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL28340810 | 0.85 | POLB (0.65) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL28340811 | 0.85 | POLB (0.65) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL9464627 | 0.84 | POLB (0.88) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL19329990 | 0.84 | TDP1 (0.60) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL30942024 | 0.83 | POLB (0.67) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL22072359 | 0.83 | POLB (0.67) | TDP1POLBHTTHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478195-A | Method for synthesizing 1, 2-triboroalkane | 南京工业大学 | 2023-07-25 | — | — | CN | claimed |
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113121373-A | Method for synthesizing chlorambucil | 南京工业大学 | 2021-07-16 | — | — | CN | claimed |
| US-11976060-B2 | Method for preparing beta-lactam derivative | SOOCHOW UNIVERSITY (CN) | 2024-05-07 | — | — | US | disclosed |
| CN-117417253-A | Method for preparing phenyl alkyl acid ester by alkyl olefin | 常州大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-116478195-A | Method for synthesizing 1, 2-triboroalkane | 南京工业大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | disclosed |
| US-20210276986-A1 | METHOD FOR PREPARING BETA-LACTAM DERIVATIVE | SOOCHOW UNIVERSITY (CN) | 2021-09-09 | — | — | US | disclosed |
| US-20210276986-A1 | METHOD FOR PREPARING BETA-LACTAM DERIVATIVE | SOOCHOW UNIVERSITY (CN) | 2021-09-09 | — | — | US | disclosed |
| CN-113150018-A | Four-coordination N, N-chelating monoaryl monofluoroborate compound and preparation method thereof | 石河子大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-113121373-A | Method for synthesizing chlorambucil | 南京工业大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-113121373-A | Method for synthesizing chlorambucil | 南京工业大学 | 2021-07-16 | — | — | CN | disclosed |
| WO-2020114025-A1 | PREPARATION METHOD FOR β-LACTAM DERIVATIVES | 苏州大学 | 2020-06-11 | — | — | WO | disclosed |
| WO-2020114025-A1 | PREPARATION METHOD FOR β-LACTAM DERIVATIVES | 苏州大学 | 2020-06-11 | — | — | WO | disclosed |
| CN-109369629-B | β -lactam derivatives and process for their preparation | 苏州大学 | 2020-04-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276986-A1 | METHOD FOR PREPARING BETA-LACTAM DERIVATIVE | TBCB, QDPR, UBE2B | TDP1 2769/4885POLB 249/4885HTT 3974/4885 |
| US-11976060-B2 | Method for preparing beta-lactam derivative | TBCB, QDPR, UBE2B | TDP1 2769/4885POLB 249/4885HTT 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.